Polyclonal Antibodies Pneumococci with Monoclonal and Rapid Multiplex Assay for Serotyping
نویسندگان
چکیده
منابع مشابه
Rapid multiplex assay for serotyping pneumococci with monoclonal and polyclonal antibodies.
We have developed and characterized a rapid semiautomated pneumococcal serotyping system incorporating a pneumococcal lysate preparation protocol and a multiplex serotyping assay. The lysate preparation incorporates a bile solubility test to confirm pneumococcal identification that also enhances assay specificity. The multiplex serotyping assay consists of 24 assays specific for 36 serotypes: s...
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Traditional confirmation procedures for the identification of a pneumococcal serotype require an isolate. Non-culture-based confirmation protocols are available. Some of these confirm only the presence of pneumococci, and others are capable of identifying a limited number of serotypes. The increased use of pneumococcal polysaccharide and conjugate vaccines, especially in high-risk patient group...
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